How does SYNVISC® compare with other viscosupplements in terms of efficacy and safety? Read these documents, including clinical research and clinical trials, to find out.
Viscosupplements for Osteoarthritis Knee Pain:
A Meta-analysis Evaluating Magnitude of Pain Relief
The efficacy and tolerability of viscosupplements for the treatment of OA knee pain has been well established in a number of clinical trials. However, until recently, no analysis existed that provided physicians with insight into the magnitude of pain relief that viscosupplements provide.
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The Magnitude of Pain Relief with SYNVISC® (hylan G-F 20) as Demonstrated in 3 Well-controlled Trials
Included in guidelines for the treatment of OA knee pain1,2 viscosupplementation has become an established therapy in the United States. Somewhat less established, however, may be the criteria that physicians must consider when determining which viscosupplement to use. These criteria may include efficacy and safety profiles, clinical experience and treatment schedule.
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Clarifying Tolerability Issues in Viscosupplementation for Osteoarthritis Knee Pain
Numerous well-controlled clinical trials, as well as a retrospective chart review, have shown that treatment for OA knee pain with SYNVISC (hylan G-F 20) has a low incidence of local adverse events — an incidence consistent with current product labeling.1,2,3,4 However, the frequency, severity and management of these events have been a subject of some discussion among clinicians.
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