Repeat Treatment

Your patients may ask about receiving SYNVISC again after experiencing up to six months of pain relief. They may also inquire about the safety of another course of treatment.

SYNVISC has a proven safety profile for both first and repeat courses of treatment.1,2 Local adverse events for viscosupplements are usually pain and/or swelling in the injected knee.


1. Kemper F, Gebhardt U, Meng T, Murray C. Tolerability and short-term effectiveness of hylan G-F 20 in 4253 patients with osteoarthritis of the knee in clinical practice. Curr Med Res Opin. 2005;21(8):1261-1269


2. Waddell DD, Bricker DC. Hylan G-F 20 tolerability with repeat treatment in a large orthopedic practice: a retrospective review. J Surg Orthop Adv. 2006;15(1):53-59